Desmoplastic Mesothelioma (DMM) is a cell subtype of Mesothelioma that occurs in the pleura and occasionally in the peritoneum.
Desmoplastic Mesothelioma is classified as a fairly common variation of Sarcomatoid Mesothelioma which is a very aggressive cell type.
Some cases of Desmoplastic Mesothelioma with biphasic and epithelial cells are diagnosed on rare occasions.
Desmoplastic Mesothelioma is a rare subtype that represents 5 to 10 % of all Mesothelioma cases.
Desmoplastic Mesothelioma cells are described as plain or “patternless” in appearance and are usually found once they have invaded the chest wall tissue.
Desmoplastic Mesothelioma is usually has a poor prognosis with a life expectancy following diagnosis is usually less than 1 year.
Diagnosing Desmoplastic Mesothelioma
When diagnosing Desmoplastic Mesothelioma, physiciansare recommend taking a large tissue biopsy so that enough cells can be examined. A large biopsy is recommended in diagnosing the Desmoplastic subtype because fibrous areas of this tumor type can often hide cell variations that are important to a Desmoplastic Mesothelioma diagnosis.
Desmoplastic malignant Mesothelioma is sometimes misdiagnosed as, pleural fibrosis, rheumatoid disease, fibrous pleurisy and spindle cell sarcoma.
When Desmoplastic Mesothelioma metastasizes, it can look plain and can be confused as benign fibrous tissue. Imaging scans like a MRI and CT scans help doctors identify its spread to the lung or chest wall.
In a study that analyzed more than 700 cases of malignant Mesothelioma from 1998 to 2002, the Desmoplastic subtype was diagnosed in only 2 percent of cases.
Doctors have specific criteria they look for when a patient is suspected of having Desmoplastic Mesothelioma which includes:
- 50 % of the tumor must be made up of dense fibrous tissue that commonly forms nodules
- Cells affected have Sarcomatoid Mesothelioma characteristics
- Necrosis, known as specific areas of cell death, are seen in 70 % of cases
- Neoplastic spindle cells spread of to the chest wall or lungs
- Cells Metastasize to nearby fatty tissue, skeletal muscles and/ or lungs
- Presence of the P53 tumor suppressor gene protein
Symptoms, Treatment and Prognosis for Desmoplastic Mesothelioma
The primary symptom of Desmoplastic Mesothelioma is chest pain caused by a buildup of fluid in the lungs.
Treatment for Desmoplastic Mesothelioma is typically palliative aimed to reduce symptoms, prolong survival rate and improve a patient’s quality of life without taking aggressive action.
Common treatments for Desmoplastic Mesothelioma can include the use of radiation and chemotherapy shrink tumors and kill cancerous cells.
A pleurodesis or paracentesis may be recommended to extract excess fluid from the lungs, chest or abdomen.
Desmoplastic Mesothelioma patients looking for new ways of treating their cancer should consider clinical trials and alternative therapies.
Desmoplastic Mesothelioma has been linked to workplace asbestos exposure.
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Cystic Mesothelioma has been linked to workplace asbestos exposure.
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Malignant Mesothelioma is rare form of cancer that affects lining of the lungs, abdomen, heart, and major organs in the body. Mesothelioma is a disease in which malignant cancer cells are found in the sac lining the chest (pleura) or the abdomen (peritoneum). There are about 3,000 new malignant Mesothelioma cases diagnosed each year in the U. S. If you are experiencing any Mesothelioma symptoms you should contact a doctor immediately.
Diagnosed With Mesothelioma?
If you or a family member has been diagnosed with malignant Mesothelioma you are going to have a lot of questions about living with Mesothelioma and what legal options you have against asbestos manufacturers and asbestos companies for your asbestos exposure. Mesothelioma is a seriously deadly disease. According to the American Cancer Society with the average survival time for people with Mesothelioma is 4-18 months.
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Family Member Died From Mesothelioma?
If you have a family member that has died from Mesothelioma cancer you should immediately consult with an experienced Mesothelioma diagnosis lawyer about what compensation may be available to you from asbestos trust funds that total more than 30 billion dollars.
It is VERY IMPORTANT that you file your Mesothelioma claim within your states Statute of Limitations.
We have seen many families lose their right to file a lawsuit because their Statute of Limitations had expired while they were grieving. We know it is a tough time to grieve the loss of a loved one, but please do not let your Statute of Limitations expire for filing your Mesothelioma lawsuit. In most states the Statute of Limitations is 2-3 years. Some states have 6 year Statute of Limitations.
Mesothelioma Latency Period
Mesothelioma has a long latency period of 10-50 years. Many Veterans, Shipyard Workers, Construction Workers, Power Plant Workers, Mill Workers, Steel Workers, Railroad Workers, Pipefitters, Insulators, Electricians, Carpenters, Welders, Auto Mechanics, Veterans, Factory Workers, and laborers are living in the early stages of a variety of asbestos related diseases. Many Mesothelioma lawyers will not accept asbestosis, asbestos lung cancer, pleural plaques, pleural thickening, colon cancer and esophageal cancer cases.
There is More Than 30 Billion Dollars Set Aside for Mesothelioma and Asbestos Victims in Asbestos Bankruptcy Trusts
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